Biological Classification Technical Classification Random Families
Speed of Evolution Low complexity regions/repeats Domain shuffling/evolution Multigene families/Paralogy HGT Pangenomes Alignment Quality pN/pS
Low High
Metazoan
Bacteria
Low High Low High
Split hand/Split foot 1
 
PHd Finger family
 
Vomeromodulin
 
PLUNC proteins
 
Transient receptorchannel
 
Ionotropic glutamate receptors
 
Phophodiesterase 4D inter. pro.
 
Vitellogenin
 
LIM domain kinase
 
Otoferlin
 
Sec13
 
Retinitis pigmentosa
 
Ankyrin repeat
Osteoclast protein
 
Dilute myosin heavy chain
 
Myosin heavy chain
 
GPS domain-containing GPCRs
 
Leucine-rich repeat
Laminin alpha
 
Thrombospondin protein
 
Low-density lipoprotein receptors
 
FOG- Immunoglobin and related proteins
 
RNA helicase BRR2
 
GPCR hormone receptors
 
Tyrosine-protein kinase
Cytochrome P450
Carbonyl reductases
ATP-binding cassette
Pyruvate dehydrogenase kinases
C4-dicarboxylate transporter
 
Uncharacterized (glycolate and propanediol) protein
 
Predicted GTPase, probable translation factor
 
Predicted enzyme of the cupin superfamily
 
Na+/glutamate symporter
 
Cysteinyl-tRNA synthetase
 
ABC-type metal ion transport system
 
Formate hydrogenlyase
 
ABC-type transport system
 
Methanol dehydrogenase
 
Sugar transferases
 
Osmosensitive K+ channel histidine kinase
 
Phosphoheptose isomerase
 
Restriction-modification, methyltrans. subunit
 
Restriction endonuclease
 
Precorrin-2 methylase
 
Collagen type IV alpha chain
 
Fillagrin
GATA 1/2/3
 
Mucins
 
Chitinase
TRAF4
 
FGFR1/2/3/4
 
Serine/threonine-protein kinase
 
Ski oncogene protein
 
Ataxin-7-like protein
 
Ribosomal protein S12
Predicted ATP-dependent serine protease
 
Membrane GTPase involved in stress response
 
Predicted ATPase (AAA+ superfamily)
 
Phosphotransacetylase
 
DNA polymerase III, alpha subunit
 
Helicase subunit of DNA excision repair
 
Ribosomal protein L13
 
Cobalamin biosynthesis protein CbiG
 
XdhC/CoxF family
 
Membrane metal-binding protein
 
Uncharacterized MobA-related protein
 
Signal transduction histidine kinase
 
Transposase and inactivated derivatives
 
FOG: Transposase and inactivated derivatives
 
Ribosomal protein L11
Methionine-R-sulfoxide reductase
Erythropoietin 4
 
Proline oxidase
Peroxisomal multifunctional enzyme
Ribosomal protein L37AE/L43A
 
S-adenosylmethionine synthetase isoform
Ribosomal protein S27E
 
Glutamate formiminotransferase
 
Alcohol dehydrogenase
Adenine phosphoribosyl transferase
 
Neurotensin receptor 3
 
Dystroglycan 1
 
Tyrosinase
 
C8orf13
 
Centrosomal protein
 
C1orf43
 
Tumor necrosis factor receptor superfamily
 
C6orf170
 
Calcium channel gamma subunits
 
Thyroid hormone receptor-associated protein
 
Glutathione S-transferase
Prokineticin 1
 
Serum response factor binding protein
 
Zinc finger, FYVE domain containing
 
C22orf25
Mitogen-activated protein
 
Pecanex
 
Corticotropin and Urocortin proteins
 
Histone deacetylase 3