Alcohol dehydrogenase, ADHFE1: (Random Families > RefOG050) - The enzymes in this ROG catalyze the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG).
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