Histone deacetylase 3: (Random Families > RefOG070) - Histone deacetylases (HDAC) (EC number 3.5.1) are a class of enzymes that remove acetyl groups from an -N-acetyl lysine amino acid on a histone. HDACs, are classified in four classes depending on sequence identity and domain organization. HD3 belongs to class I with the HD2, HD1 and HD8. HD3 is found in both the nucleus and the cytoplasm, while the rest class I enzymes are located primarily to nucleus.
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