eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups) is a database of orthologous groups of genes. The orthologous groups are annotated with functional description lines (derived by identifying a common denominator for the genes based on their various annotations), with functional categories (i.e derived from the original COG/KOG categories).
eggNOG's database currently counts 721,801 orthologous groups in 1133 species, covering 4,396,591 proteins (built from 5,214,234 proteins).
eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges.
Powell S, Szklarczyk D, Trachana K, Roth A, Kuhn M, Muller J, Arnold R, Rattei T, Letunic I, Doerks T, Jensen LJ, von Mering C, Bork P
Nucleic Acids Res.
Epub 2011 Nov 16; PubMed 22096231.
EMBL - European Molecular Biology Laboratory
SIB - Swiss Institute of Bioinformatics
UZH - University of Zurich
BMBF - German Ministry of Education and Research
EMBO - European Molecular Biology Organization
ProBioC - Foundation ProBioC (Heidelberg)
FP6 - EU 6th Framework Program
Trying to reproduce an earlier finding? Confused? Refer to our previous releases:
eggNOG version 1.0
eggNOG version 2.0
Apart from in-house predictions and transfers, eggNOG also relies on many fine resources maintained elsewhere:
...and many others.
Their input and support are gratefully acknowledged.