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eggNOG uses a relational database system (PostgreSQL) to store primary data and precomputed orthologous groups. For convenience, we provide selected data-items as flatfiles below. FTP access to all files is also provided.
General Files
species.v3.txt Organisms in eggNOG
protein.aliases.v3.txt.gz (375 MB) Aliases for eggNOG proteins: locus names, accessions, descriptions...
fun.txt.gz Description of the functional categories (Tatusov et al Science 1997)
UniProtAC2eggNOG.3.0.tsv.gz (16 MB) Assignments of Uniprot ID to COGs and NOGs
levels.txt Definition of all 41 levels in eggNOG version 3.0
sequences.v3.tar.gz (1.1 GB) Protein sequences of all species, with the eggnog protein name. (tax_id.protein_id)
sequences.raw.v3.tar.gz (1.3 GB) Protein sequences of all species with the original annotation.
Orthologous groups (flatfiles)
all.members.tar.gz (146 MB) All COGs, KOGs, arCOGs and non-supervised orthologous groups and their proteins
aciNOG.members.txt.gz Acidobacteria non-supervised orthologous groups (aciNOG) and their proteins
actNOG.members.txt.gz Actinobacteria non-supervised orthologous groups (actNOG) and their proteins
aproNOG.members.txt.gz Alpha-proteobacteria non-supervised orthologous groups (aproNOG) and their proteins
aquiNOG.members.txt.gz Aquificales non-supervised orthologous groups (aquiNOG) and their proteins
arCOG.members.txt.gz Archaeal clusters of orthologous groups (arCOG) and their proteins
arNOG.members.txt.gz Archaea non-supervised orthologous groups (arNOG) and their proteins
bactNOG.members.txt.gz (23 MB) Bacteria non-supervised orthologous groups (bactNOG) and their proteins
bctoNOG.members.txt.gz Bacteroidetes non-supervised orthologous groups (bctoNOG) and their proteins
biNOG.members.txt.gz Bilateria non-supervised orthologous groups (biNOG) and their proteins
bproNOG.members.txt.gz Beta-proteobacteria non-supervised orthologous groups (bproNOG) and their proteins
chlaNOG.members.txt.gz Chlamydiae non-supervised orthologous groups (chlaNOG) and their proteins
chlNOG.members.txt.gz Chlorobi non-supervised orthologous groups (chlNOG) and their proteins
chloNOG.members.txt.gz Chloroflexi non-supervised orthologous groups (chloNOG) and their proteins
chorNOG.members.txt.gz Chordata non-supervised orthologous groups (chorNOG) and their proteins
COG.members.txt.gz (28 MB) Clusters of orthologous groups (COG) and their proteins. For the complete set of orthologous groups in LUCA consider the NOGs as well.
creNOG.members.txt.gz Crenarchaeota non-supervised orthologous groups (creNOG) and their proteins
cyaNOG.members.txt.gz Cynobacteria non-supervised orthologous groups (cyaNOG) and their proteins
deiNOG.members.txt.gz Deinococcus-thermus non-supervised orthologous groups (deiNOG) and their proteins
dicNOG.members.txt.gz Dictyoglomi non-supervised orthologous groups (dicNOG) and their proteins
dproNOG.members.txt.gz Delta-proteobacteria non-supervised orthologous groups (dproNOG) and their proteins
eproNOG.members.txt.gz Epsilon-proteobacteria non-supervised orthologous groups (eproNOG) and their proteins
euNOG.members.txt.gz Eukaryotes non-supervised orthologous groups (euNOG) and their proteins. For the complete set of eukaryotic orthologous groups consider the KOGs as well.
eurNOG.members.txt.gz Euryarchaeota non-supervised orthologous groups (eurNOG) and their proteins
fiNOG.members.txt.gz Fishes non-supervised orthologous groups (fiNOG) and their proteins
firmNOG.members.txt.gz Firmicutes non-supervised orthologous groups (firmNOG) and their proteins
fuNOG.members.txt.gz Fungi non-supervised orthologous groups (fuNOG) and their proteins
fusoNOG.members.txt.gz Fusobacteria non-supervised orthologous groups (fusoNOG) and their proteins
gproNOG.members.txt.gz Gamma-proteobacteria non-supervised orthologous groups (gproNOG) and their proteins
inNOG.members.txt.gz Insects non-supervised orthologous groups (inNOG) and their proteins
KOG.members.txt.gz Eukaryote clusters of orthologous groups (KOG) and their proteins. For the complete set of eukaryotic orthologous groups consider the euNOGs as well.
maNOG.members.txt.gz Mammals non-supervised orthologous groups (maNOG) and their proteins
meNOG.members.txt.gz Animals non-supervised orthologous groups (meNOG) and their proteins
nemNOG.members.txt.gz Nematodes non-supervised orthologous groups (nemNOG) and their proteins
NOG.members.txt.gz (15 MB) Non-supervised orthologous groups (NOG) and their proteins. For the complete set of orthologous groups in LUCA consider the COGs as well.
opiNOG.members.txt.gz Opisthokonts non-supervised orthologous groups (opiNOG) and their proteins
prNOG.members.txt.gz Primates non-supervised orthologous groups (prNOG) and their proteins
proNOG.members.txt.gz (13 MB) Proteobacteria non-supervised orthologous groups (proNOG) and their proteins
roNOG.members.txt.gz Rodents non-supervised orthologous groups (roNOG) and their proteins
spiNOG.members.txt.gz Spirochaetes non-supervised orthologous groups (spiNOG) and their proteins
spriNOG.members.txt.gz Supraprimates non-supervised orthologous groups (spriNOG) and their proteins
tenNOG.members.txt.gz Tenericutes non-supervised orthologous groups (tenNOG) and their proteins
therNOG.members.txt.gz Thermotogae non-supervised orthologous groups (therNOG) and their proteins
veNOG.members.txt.gz Vertebrates non-supervised orthologous groups (veNOG) and their proteins
verNOG.members.txt.gz Verrucomicrobia non-supervised orthologous groups (verNOG) and their proteins
Functional description assignment
all.description.tar.gz All non-supervised orthologous groups and their functional description
aciNOG.description.txt.gz Acidobacteria non-supervised orthologous groups (aciNOG) and their functional description
actNOG.description.txt.gz Actinobacteria non-supervised orthologous groups (actNOG) and their functional description
aproNOG.description.txt.gz Alpha-proteobacteria non-supervised orthologous groups (aproNOG) and their functional description
aquiNOG.description.txt.gz Aquificales non-supervised orthologous groups (aquiNOG) and their functional description
arCOG.description.txt.gz Archaeal clusters of orthologous groups (arCOG) and their functional description
arNOG.description.txt.gz Archaea non-supervised orthologous groups (arNOG) and their functional description
bactNOG.description.txt.gz Bacteria non-supervised orthologous groups (bactNOG) and their functional description
bctoNOG.description.txt.gz Bacteroidetes non-supervised orthologous groups (bctoNOG) and their functional description
biNOG.description.txt.gz Bilateria non-supervised orthologous groups (biNOG) and their functional description
bproNOG.description.txt.gz Beta-proteobacteria non-supervised orthologous groups (bproNOG) and their functional description
chlaNOG.description.txt.gz Chlamydiae non-supervised orthologous groups (chlaNOG) and their functional description
chlNOG.description.txt.gz Chlorobi non-supervised orthologous groups (chlNOG) and their functional description
chloNOG.description.txt.gz Chloroflexi non-supervised orthologous groups (chloNOG) and their functional description
chorNOG.description.txt.gz Chordata non-supervised orthologous groups (chorNOG) and their functional description
COG.description.txt.gz Clusters of orthologous groups (COG) and their functional description
creNOG.description.txt.gz Crenarchaeota non-supervised orthologous groups (creNOG) and their functional description
cyaNOG.description.txt.gz Cynobacteria non-supervised orthologous groups (cyaNOG) and their functional description
deiNOG.description.txt.gz Deinococcus-thermus non-supervised orthologous groups (deiNOG) and their functional description
dicNOG.description.txt.gz Dictyoglomi non-supervised orthologous groups (dicNOG) and their functional description
dproNOG.description.txt.gz Delta-proteobacteria non-supervised orthologous groups (dproNOG) and their functional description
eproNOG.description.txt.gz Epsilon-proteobacteria non-supervised orthologous groups (eproNOG) and their functional description
euNOG.description.txt.gz Eukaryotes non-supervised orthologous groups (euNOG) and their functional description
eurNOG.description.txt.gz Euryarchaeota non-supervised orthologous groups (eurNOG) and their functional description
fiNOG.description.txt.gz Fishes non-supervised orthologous groups (fiNOG) and their functional description
firmNOG.description.txt.gz Firmicutes non-supervised orthologous groups (firmNOG) and their functional description
fuNOG.description.txt.gz Fungi non-supervised orthologous groups (fuNOG) and their functional description
fusoNOG.description.txt.gz Fusobacteria non-supervised orthologous groups (fusoNOG) and their functional description
gproNOG.description.txt.gz Gamma-proteobacteria non-supervised orthologous groups (gproNOG) and their functional description
inNOG.description.txt.gz Insects non-supervised orthologous groups (inNOG) and their functional description
KOG.description.txt.gz Eukaryote clusters of orthologous groups (KOG) and their functional description
maNOG.description.txt.gz Mammals non-supervised orthologous groups (maNOG) and their functional description
meNOG.description.txt.gz Animals non-supervised orthologous groups (meNOG) and their functional description
nemNOG.description.txt.gz Nematodes non-supervised orthologous groups (nemNOG) and their functional description
NOG.description.txt.gz Non-supervised orthologous groups (NOG) and their functional description
opiNOG.description.txt.gz Opisthokonts non-supervised orthologous groups (opiNOG) and their functional description
prNOG.description.txt.gz Primates non-supervised orthologous groups (prNOG) and their functional description
proNOG.description.txt.gz Proteobacteria non-supervised orthologous groups (proNOG) and their functional description
roNOG.description.txt.gz Rodents non-supervised orthologous groups (roNOG) and their functional description
spiNOG.description.txt.gz Spirochaetes non-supervised orthologous groups (spiNOG) and their functional description
spriNOG.description.txt.gz Supraprimates non-supervised orthologous groups (spriNOG) and their functional description
tenNOG.description.txt.gz Tenericutes non-supervised orthologous groups (tenNOG) and their functional description
therNOG.description.txt.gz Thermotogae non-supervised orthologous groups (therNOG) and their functional description
veNOG.description.txt.gz Vertebrates non-supervised orthologous groups (veNOG) and their functional description
verNOG.description.txt.gz Verrucomicrobia non-supervised orthologous groups (verNOG) and their functional description
Functional categories assignment (as defined by Tatusov et al Science 1997)
all.funccat.tar.gz All non-supervised orthologous groups and their functional category
aciNOG.funccat.txt.gz Acidobacteria non-supervised orthologous groups (aciNOG) and their functional category
actNOG.funccat.txt.gz Actinobacteria non-supervised orthologous groups (actNOG) and their functional category
aproNOG.funccat.txt.gz Alpha-proteobacteria non-supervised orthologous groups (aproNOG) and their functional category
aquiNOG.funccat.txt.gz Aquificales non-supervised orthologous groups (aquiNOG) and their functional category
arCOG.funccat.txt.gz Archaeal clusters of orthologous groups (arCOG) and their functional category
arNOG.funccat.txt.gz Archaea non-supervised orthologous groups (arNOG) and their functional category
bactNOG.funccat.txt.gz Bacteria non-supervised orthologous groups (bactNOG) and their functional category
bctoNOG.funccat.txt.gz Bacteroidetes non-supervised orthologous groups (bctoNOG) and their functional category
biNOG.funccat.txt.gz Bilateria non-supervised orthologous groups (biNOG) and their functional category
bproNOG.funccat.txt.gz Beta-proteobacteria non-supervised orthologous groups (bproNOG) and their functional category
chlaNOG.funccat.txt.gz Chlamydiae non-supervised orthologous groups (chlaNOG) and their functional category
chlNOG.funccat.txt.gz Chlorobi non-supervised orthologous groups (chlNOG) and their functional category
chloNOG.funccat.txt.gz Chloroflexi non-supervised orthologous groups (chloNOG) and their functional category
chorNOG.funccat.txt.gz Chordata non-supervised orthologous groups (chorNOG) and their functional category
COG.funccat.txt.gz Clusters of orthologous groups (COG) and their functional category
creNOG.funccat.txt.gz Crenarchaeota non-supervised orthologous groups (creNOG) and their functional category
cyaNOG.funccat.txt.gz Cynobacteria non-supervised orthologous groups (cyaNOG) and their functional category
deiNOG.funccat.txt.gz Deinococcus-thermus non-supervised orthologous groups (deiNOG) and their functional category
dicNOG.funccat.txt.gz Dictyoglomi non-supervised orthologous groups (dicNOG) and their functional category
dproNOG.funccat.txt.gz Delta-proteobacteria non-supervised orthologous groups (dproNOG) and their functional category
eproNOG.funccat.txt.gz Epsilon-proteobacteria non-supervised orthologous groups (eproNOG) and their functional category
euNOG.funccat.txt.gz Eukaryotes non-supervised orthologous groups (euNOG) and their functional category
eurNOG.funccat.txt.gz Euryarchaeota non-supervised orthologous groups (eurNOG) and their functional category
fiNOG.funccat.txt.gz Fishes non-supervised orthologous groups (fiNOG) and their functional category
firmNOG.funccat.txt.gz Firmicutes non-supervised orthologous groups (firmNOG) and their functional category
fuNOG.funccat.txt.gz Fungi non-supervised orthologous groups (fuNOG) and their functional category
fusoNOG.funccat.txt.gz Fusobacteria non-supervised orthologous groups (fusoNOG) and their functional category
gproNOG.funccat.txt.gz Gamma-proteobacteria non-supervised orthologous groups (gproNOG) and their functional category
inNOG.funccat.txt.gz Insects non-supervised orthologous groups (inNOG) and their functional category
KOG.funccat.txt.gz Eukaryote clusters of orthologous groups (KOG) and their functional category
maNOG.funccat.txt.gz Mammals non-supervised orthologous groups (maNOG) and their functional category
meNOG.funccat.txt.gz Animals non-supervised orthologous groups (meNOG) and their functional category
nemNOG.funccat.txt.gz Nematodes non-supervised orthologous groups (nemNOG) and their functional category
NOG.funccat.txt.gz Non-supervised orthologous groups (NOG) and their functional category
opiNOG.funccat.txt.gz Opisthokonts non-supervised orthologous groups (opiNOG) and their functional category
prNOG.funccat.txt.gz Primates non-supervised orthologous groups (prNOG) and their functional category
proNOG.funccat.txt.gz Proteobacteria non-supervised orthologous groups (proNOG) and their functional category
roNOG.funccat.txt.gz Rodents non-supervised orthologous groups (roNOG) and their functional category
spiNOG.funccat.txt.gz Spirochaetes non-supervised orthologous groups (spiNOG) and their functional category
spriNOG.funccat.txt.gz Supraprimates non-supervised orthologous groups (spriNOG) and their functional category
tenNOG.funccat.txt.gz Tenericutes non-supervised orthologous groups (tenNOG) and their functional category
therNOG.funccat.txt.gz Thermotogae non-supervised orthologous groups (therNOG) and their functional category
veNOG.funccat.txt.gz Vertebrates non-supervised orthologous groups (veNOG) and their functional category
verNOG.funccat.txt.gz Verrucomicrobia non-supervised orthologous groups (verNOG) and their functional category
Multiple Sequence Alignments
all.members.alignments.tar.gz All non-supervised orthologous groups and their alignments
aciNOG.alignments.tar.gz Acidobacteria non-supervised orthologous groups (aciNOG) and their alignments
actNOG.alignments.tar.gz Actinobacteria non-supervised orthologous groups (actNOG) and their alignments
aproNOG.alignments.tar.gz Alpha-proteobacteria non-supervised orthologous groups (aproNOG) and their alignments
aquiNOG.alignments.tar.gz Aquificales non-supervised orthologous groups (aquiNOG) and their alignments
arCOG.alignments.tar.gz Archaeal clusters of orthologous groups (arCOG) and their alignments
arNOG.alignments.tar.gz Archaea non-supervised orthologous groups (arNOG) and their alignments
bactNOG.alignments.tar.gz Bacteria non-supervised orthologous groups (bactNOG) and their alignments
bctoNOG.alignments.tar.gz Bacteroidetes non-supervised orthologous groups (bctoNOG) and their alignments
biNOG.alignments.tar.gz Bilateria non-supervised orthologous groups (biNOG) and their alignments
bproNOG.alignments.tar.gz Beta-proteobacteria non-supervised orthologous groups (bproNOG) and their alignments
chlaNOG.alignments.tar.gz Chlamydiae non-supervised orthologous groups (chlaNOG) and their alignments
chlNOG.alignments.tar.gz Chlorobi non-supervised orthologous groups (chlNOG) and their alignments
chloNOG.alignments.tar.gz Chloroflexi non-supervised orthologous groups (chloNOG) and their alignments
chorNOG.alignments.tar.gz Chordata non-supervised orthologous groups (chorNOG) and their alignments
COG.alignments.tar.gz Clusters of orthologous groups (COG) and their alignments
creNOG.alignments.tar.gz Crenarchaeota non-supervised orthologous groups (creNOG) and their alignments
cyaNOG.alignments.tar.gz Cynobacteria non-supervised orthologous groups (cyaNOG) and their alignments
deiNOG.alignments.tar.gz Deinococcus-thermus non-supervised orthologous groups (deiNOG) and their alignments
dicNOG.alignments.tar.gz Dictyoglomi non-supervised orthologous groups (dicNOG) and their alignments
dproNOG.alignments.tar.gz Delta-proteobacteria non-supervised orthologous groups (dproNOG) and their alignments
eproNOG.alignments.tar.gz Epsilon-proteobacteria non-supervised orthologous groups (eproNOG) and their alignments
euNOG.alignments.tar.gz Eukaryotes non-supervised orthologous groups (euNOG) and their alignments
eurNOG.alignments.tar.gz Euryarchaeota non-supervised orthologous groups (eurNOG) and their alignments
fiNOG.alignments.tar.gz Fishes non-supervised orthologous groups (fiNOG) and their alignments
firmNOG.alignments.tar.gz Firmicutes non-supervised orthologous groups (firmNOG) and their alignments
fuNOG.alignments.tar.gz Fungi non-supervised orthologous groups (fuNOG) and their alignments
fusoNOG.alignments.tar.gz Fusobacteria non-supervised orthologous groups (fusoNOG) and their alignments
gproNOG.alignments.tar.gz Gamma-proteobacteria non-supervised orthologous groups (gproNOG) and their alignments
inNOG.alignments.tar.gz Insects non-supervised orthologous groups (inNOG) and their alignments
KOG.alignments.tar.gz Eukaryote clusters of orthologous groups (KOG) and their alignments
maNOG.alignments.tar.gz Mammals non-supervised orthologous groups (maNOG) and their alignments
meNOG.alignments.tar.gz Animals non-supervised orthologous groups (meNOG) and their alignments
nemNOG.alignments.tar.gz Nematodes non-supervised orthologous groups (nemNOG) and their alignments
NOG.alignments.tar.gz Non-supervised orthologous groups (NOG) and their alignments
opiNOG.alignments.tar.gz Opisthokonts non-supervised orthologous groups (opiNOG) and their alignments
prNOG.alignments.tar.gz Primates non-supervised orthologous groups (prNOG) and their alignments
proNOG.alignments.tar.gz Proteobacteria non-supervised orthologous groups (proNOG) and their alignments
roNOG.alignments.tar.gz Rodents non-supervised orthologous groups (roNOG) and their alignments
spiNOG.alignments.tar.gz Spirochaetes non-supervised orthologous groups (spiNOG) and their alignments
spriNOG.alignments.tar.gz Supraprimates non-supervised orthologous groups (spriNOG) and their alignments
tenNOG.alignments.tar.gz Tenericutes non-supervised orthologous groups (tenNOG) and their alignments
veNOG.alignments.tar.gz Vertebrates non-supervised orthologous groups (veNOG) and their alignments
verNOG.alignments.tar.gz Verrucomicrobia non-supervised orthologous groups (verNOG) and their alignments
Phylogenetic Trees
all.members.trees.tar.gz All non-supervised orthologous groups and their trees
aciNOG.trees.tar.gz Acidobacteria non-supervised orthologous groups (aciNOG) and their trees
actNOG.trees.tar.gz Actinobacteria non-supervised orthologous groups (actNOG) and their trees
aproNOG.trees.tar.gz Alpha-proteobacteria non-supervised orthologous groups (aproNOG) and their trees
aquiNOG.trees.tar.gz Aquificales non-supervised orthologous groups (aquiNOG) and their trees
arCOG.trees.tar.gz Archaeal clusters of orthologous groups (arCOG) and their trees
arNOG.trees.tar.gz Archaea non-supervised orthologous groups (arNOG) and their trees
bactNOG.trees.tar.gz Bacteria non-supervised orthologous groups (bactNOG) and their trees
bctoNOG.trees.tar.gz Bacteroidetes non-supervised orthologous groups (bctoNOG) and their trees
biNOG.trees.tar.gz Bilateria non-supervised orthologous groups (biNOG) and their trees
bproNOG.trees.tar.gz Beta-proteobacteria non-supervised orthologous groups (bproNOG) and their trees
chlaNOG.trees.tar.gz Chlamydiae non-supervised orthologous groups (chlaNOG) and their trees
chlNOG.trees.tar.gz Chlorobi non-supervised orthologous groups (chlNOG) and their trees
chloNOG.trees.tar.gz Chloroflexi non-supervised orthologous groups (chloNOG) and their trees
chorNOG.trees.tar.gz Chordata non-supervised orthologous groups (chorNOG) and their trees
COG.trees.tar.gz Clusters of orthologous groups (COG) and their trees
creNOG.trees.tar.gz Crenarchaeota non-supervised orthologous groups (creNOG) and their trees
cyaNOG.trees.tar.gz Cynobacteria non-supervised orthologous groups (cyaNOG) and their trees
deiNOG.trees.tar.gz Deinococcus-thermus non-supervised orthologous groups (deiNOG) and their trees
dicNOG.trees.tar.gz Dictyoglomi non-supervised orthologous groups (dicNOG) and their trees
dproNOG.trees.tar.gz Delta-proteobacteria non-supervised orthologous groups (dproNOG) and their trees
eproNOG.trees.tar.gz Epsilon-proteobacteria non-supervised orthologous groups (eproNOG) and their trees
euNOG.trees.tar.gz Eukaryotes non-supervised orthologous groups (euNOG) and their trees
eurNOG.trees.tar.gz Euryarchaeota non-supervised orthologous groups (eurNOG) and their trees
fiNOG.trees.tar.gz Fishes non-supervised orthologous groups (fiNOG) and their trees
firmNOG.trees.tar.gz Firmicutes non-supervised orthologous groups (firmNOG) and their trees
fuNOG.trees.tar.gz Fungi non-supervised orthologous groups (fuNOG) and their trees
fusoNOG.trees.tar.gz Fusobacteria non-supervised orthologous groups (fusoNOG) and their trees
gproNOG.trees.tar.gz Gamma-proteobacteria non-supervised orthologous groups (gproNOG) and their trees
inNOG.trees.tar.gz Insects non-supervised orthologous groups (inNOG) and their trees
KOG.trees.tar.gz Eukaryote clusters of orthologous groups (KOG) and their trees
maNOG.trees.tar.gz Mammals non-supervised orthologous groups (maNOG) and their trees
meNOG.trees.tar.gz Animals non-supervised orthologous groups (meNOG) and their trees
nemNOG.trees.tar.gz Nematodes non-supervised orthologous groups (nemNOG) and their trees
NOG.trees.tar.gz Non-supervised orthologous groups (NOG) and their trees
opiNOG.trees.tar.gz Opisthokonts non-supervised orthologous groups (opiNOG) and their trees
prNOG.trees.tar.gz Primates non-supervised orthologous groups (prNOG) and their trees
proNOG.trees.tar.gz Proteobacteria non-supervised orthologous groups (proNOG) and their trees
roNOG.trees.tar.gz Rodents non-supervised orthologous groups (roNOG) and their trees
spiNOG.trees.tar.gz Spirochaetes non-supervised orthologous groups (spiNOG) and their trees
spriNOG.trees.tar.gz Supraprimates non-supervised orthologous groups (spriNOG) and their trees
tenNOG.trees.tar.gz Tenericutes non-supervised orthologous groups (tenNOG) and their trees
therNOG.trees.tar.gz Thermotogae non-supervised orthologous groups (therNOG) and their trees
veNOG.trees.tar.gz Vertebrates non-supervised orthologous groups (veNOG) and their trees
verNOG.trees.tar.gz Verrucomicrobia non-supervised orthologous groups (verNOG) and their trees